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Trizivir (abacavir/lamivudine/zidovudine)

Indications

Trizivir is used in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and adolescents. It helps to lower the amount of HIV in the body, keeping the immune system healthy and reducing the risk of complications.

Ingredients

  • Active Ingredients: Abacavir, lamivudine, zidovudine.
  • Inactive Ingredients: Magnesium stearate, microcrystalline cellulose, sodium starch glycolate, titanium dioxide, polysorbate 80, and colorants.

Dosage and Administration

  • Take Trizivir exactly as prescribed by your healthcare provider, usually one tablet twice daily, with or without food.
  • Swallow the tablet whole with water; do not crush, chew, or break the tablet to ensure proper dosing.
  • Stay hydrated by drinking plenty of fluids throughout the day. If you miss a dose, take it as soon as you remember, unless it’s close to your next dose; in that case, skip the missed dose and continue with your regular schedule.
  • Do not take Trizivir if you have tested positive for the HLA-B*5701 allele due to the risk of severe hypersensitivity reactions.
  • Avoid drinking alcohol while taking Trizivir, as it can increase the risk of side effects such as liver damage.
  • Do not stop taking Trizivir without consulting your healthcare provider, as this can worsen your condition or lead to drug resistance.

Mechanism of Action

Trizivir combines three antiretroviral agents: abacavir, lamivudine, and zidovudine. These drugs inhibit the activity of reverse transcriptase, an enzyme crucial for the replication of HIV. By blocking this enzyme, Trizivir prevents the virus from multiplying, thereby reducing the viral load in the blood and helping to maintain immune function.

Contraindications

  • Severe Hypersensitivity Reactions: Trizivir is contraindicated in patients with a history of severe hypersensitivity to abacavir, lamivudine, or zidovudine. Symptoms may include rash, fever, nausea, vomiting, and respiratory issues.
  • Liver Disease: Do not use Trizivir if you have moderate or severe liver impairment, as it can exacerbate liver dysfunction.
  • Low White Blood Cell or Hemoglobin Counts: Trizivir is not recommended for patients with significantly low levels of white blood cells or hemoglobin due to the risk of severe bone marrow suppression.

Side Effects

Common Side Effects:

  • Nausea
  • Headache
  • Fatigue
  • Diarrhea
  • Insomnia

Serious Side Effects:

  • Severe hypersensitivity reactions (e.g., rash, fever, organ dysfunction)
  • Lactic acidosis (symptoms include muscle pain, shortness of breath, stomach pain, irregular heartbeat)
  • Liver toxicity (e.g., jaundice, dark urine, severe abdominal pain)
  • Bone marrow suppression (e.g., anemia, low white blood cell counts)

Precautions

  • Hypersensitivity Screening: Ensure you are screened for the HLA-B*5701 allele before starting Trizivir to avoid severe hypersensitivity reactions.
  • Monitor Blood Counts: Regularly monitor your blood counts, as Trizivir can cause anemia or a decrease in white blood cells.
  • Lactic Acidosis and Hepatomegaly: Watch for signs of lactic acidosis and liver problems, such as persistent nausea, vomiting, abdominal pain, or jaundice.
  • Cardiovascular Health: Inform your healthcare provider if you have any history of heart disease, as abacavir has been associated with an increased risk of heart attack.

Storage Instructions

  • Store Trizivir tablets at room temperature, between 20°C and 25°C (68°F and 77°F).
  • Keep the tablets in their original container, tightly closed, and protect them from moisture and heat.
  • Store away from light and out of reach of children and pets.

Why Choose Our Online Pharmacy for Trizivir?

Authenticity and Safety

Certified Authenticity: PrescriptionPoint is accredited by CIPA and IPABC, guaranteeing that every drug we offer is genuine and safe.

Prescription Requirement: We prioritize your well-being by requiring a valid prescription from a healthcare provider, ensuring that Trizivir is suitable for your condition.

Cost and Savings

Affordable Pricing: PrescriptionPoint provides some of the most competitive prices for Trizivir online, helping you reduce your drug expenses.

Generic Alternatives: Besides the brand-name Trizivir, we offer generic Abacavir/Lamivudine/Zidovudine, which is just as effective and more budget friendly.

Customer Service

Our committed customer service team is always available to help with any questions or issues, ensuring a seamless purchasing experience.

Positive Reviews

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How to Order Trizivir Online in Canada?

Online

You can easily buy Trizivir or its generic alternative Abacavir/Lamivudine/Zidovudine on our website, www.prescriptionpoint.com.

Phone

For personalized assistance, you can place your order for Trizivir by speaking with one of our friendly customer support representatives. Just call us on +1-877-244-0431, and we will be happy to assist you.

Fax

If you prefer using fax, you can send your prescription and details to our secure fax line at +1-877-453-0921. We ensure quick and confidential processing of your order.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021205s036lbl.pdf

Additional information

Brand Name:

Trizivir

Scientific Name:

Abacavir/Lamivudine/Zidovudine

Other Names:

Trizivir

Strength(s):

300/150/300mg

Quantities Available:

60

Formulation:

Film Coated Tablet

The information above is provided by third parties to Prescriptionpoint.com for Trizivir (Abacavir/Lamivudine/Zidovudine). This information is for general purposes only and is not intended to replace a physician's advice. Always consult with your doctor or a qualified health care professional if you need advice on any medical concerns.


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