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Singulair (montelukast)

Indications

Singulair is prescribed for:

• Helping to prevent and treat asthma in individuals aged 12 months and older. 
• Preventing sudden airway narrowing during exercise in individuals aged 6 years and older. 
• Easing symptoms of nasal allergies: 
• For seasonal allergies such as hay fever, in individuals aged 2 years and older. 
• For year-round allergies, in individuals aged 6 months and older. 

Dosage and Administration

• Read the Medication Guide provided by your pharmacist before starting or refilling Singulair.
• Take Singulair by mouth with or without food, as directed by your healthcare provider.
• Take Singulair at the same time each day. For asthma or asthma and allergies: take in the evening. For allergies only: take in the morning or evening.
• Take your dose at least 2 hours before exercising if using it to prevent breathing problems during exercise.
• Do not take more than one dose in 24 hours.
• Do not take a dose before exercise if you are already taking this medication daily for asthma or allergies.
• Do not adjust your dose or discontinue the medication without consulting your healthcare provider.

Mechanism of Action

Singulair works by blocking substances in the body called leukotrienes, which cause symptoms of asthma and allergic rhinitis. By preventing leukotrienes from causing inflammation, tightening of airways, and other symptoms, Singulair helps improve breathing and reduces allergy symptoms.

Contraindications

Hypersensitivity to any component of Singulair.

Side Effects

Common Side Effects:

• Fever or flu-like symptoms 
• Headaches 
• Sore throat 
• Upper respiratory infections 
• Stomach pain 
• Runny nose 

Serious Side Effects: 

• Stuttering 
• Tremors 
• Uncontrolled muscle movements 
• Suicidal thoughts or actions 
• Hallucinations 
• Sleep problems, vivid dreams, sleepwalking 
• Compulsive or repetitive behaviors 

Precautions

• Do not use Singulair to treat an acute asthma attack. Always have appropriate rescue medication available with you.
• Do not abruptly substitute Singulair for inhaled or oral corticosteroids. Consult your doctor for a gradual reduction plan.
• If you have known aspirin sensitivity, continue to avoid aspirin or non-steroidal anti-inflammatory agents while taking Singulair.
• Be alert for neuropsychiatric events like mood changes, aggression, or depression. Evaluate risks and benefits if such events occur.
• Some patients have reported systemic eosinophilia, sometimes presenting with features of vasculitis consistent with Churg-Strauss syndrome. These events often, but not always, are associated with the reduction of oral corticosteroid therapy.
• Inform patients with phenylketonuria that the 4-mg and 5-mg chewable tablets contain phenylalanine.

Storage Instructions

Store tablets at 25°C (77°F). You can keep them in between 15-30°C (59-86°F).