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Revia (naltrexone) 

Indications 

• Revia is used as part of a comprehensive treatment program for alcohol dependence. It helps to reduce the craving for alcohol and decrease the desire to drink. 
• It is also used to prevent relapse in individuals who have stopped using opioids and are free from withdrawal symptoms. 

Dosage and Administration 

• Take Revia exactly as prescribed by your doctor. 
• Swallow the tablets whole with a full glass of water. 
• Take the medication with or without food. 
• Follow your doctor’s instructions on the dosage and schedule, typically taken once daily. 
• Do not crush, chew, or break the tablets. 
• Avoid skipping doses. 
• Do not take more than the prescribed dose to prevent potential side effects or overdose. 

Mechanism of Action 

Revia (Naltrexone) is an opioid antagonist that works by blocking the effects of opioids and alcohol in the brain. It binds to opioid receptors and prevents them from being activated, thereby reducing the rewarding effects of these substances. By blocking opioid receptors, Revia helps to decrease the craving for alcohol and opioid drugs, supporting recovery from addiction. 

Contraindications 

• Do not use it if you are allergic to Naltrexone or any ingredients in Revia. 
• Avoid use if you are currently dependent on opioids or experiencing opioid withdrawal symptoms. 
• Not recommended for use in individuals with acute hepatitis or liver failure. 
• Consult your doctor if you have a history of liver or kidney disease before taking this medication. 

Side Effects 

Common Side Effects: 

• Nausea 
• Headache 
• Dizziness 
• Fatigue 
• Anxiety 
• Insomnia 
• Muscle or joint pain 

Serious Side Effects: 

• Signs of liver problems (yellowing of the skin or eyes, dark urine, abdominal pain) 
• Allergic reactions (rash, itching, swelling of the face/tongue/throat) 
• Signs of opioid withdrawal (restlessness, muscle aches, sweating, yawning) 
• Mood changes (depression, suicidal thoughts) 
• Unusual bleeding or bruising 

Precautions 

• Regularly monitor liver function as recommended by your healthcare provider. 
• Avoid activities that require alertness until you know how Revia affects you, as it may cause dizziness or drowsiness. 
• Take Revia consistently to maintain its effectiveness in reducing alcohol or opioid cravings. 

Storage Instructions 

• Store Revia tablets at room temperature between 68°F and 77°F (20°C and 25°C). 
• Keep the medication in its original container, tightly closed, and away from moisture and light. 
• Do not store it in the bathroom to avoid exposure to humidity. 
• Keep out of reach of children and pets. 

References 

https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/018932s017lbl.pdf