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Ponstan (mefenamic acid)

Indications

• Ponstan is used to relieve mild to moderate pain from various conditions, such as headaches, dental pain, and muscle aches.
• Commonly prescribed to alleviate pain and discomfort associated with menstrual periods (dysmenorrhea).
• It helps to reduce pain, swelling, and stiffness in conditions such as osteoarthritis and rheumatoid arthritis.

Dosage and Administration

• Take Ponstan exactly as prescribed by your doctor.
• Swallow the capsules whole with a full glass of water.
• Take the medication with food or milk to minimize stomach upset.
• Follow your doctor’s advice regarding the dosage and duration of use.
• Inform your doctor of all medications and supplements you are currently taking.
• Do not crush or chew the capsules as it can affect the drug’s effectiveness.
• Avoid taking Ponstan on an empty stomach to prevent gastrointestinal irritation.
• Do not exceed the prescribed dose; taking more than recommended can increase the risk of side effects.
• Do not stop taking Ponstan abruptly without consulting your doctor, especially if used for chronic conditions.

Mechanism of Action

Ponstan (Mefenamic Acid) belongs to a class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs). It works by inhibiting the enzymes (COX-1 and COX-2) involved in the production of prostaglandins, which are chemicals responsible for inflammation, pain, and fever. By reducing the levels of prostaglandins, Ponstan helps to alleviate pain and reduce inflammation.

Contraindications

• Do not use the medication if you are allergic to Mefenamic acid or any other NSAIDs.
• Avoid if you have a history of stomach ulcers or bleeding.
• Not recommended for patients with severe kidney or liver disease.
• Consult your doctor if you have heart disease, high blood pressure, or asthma before taking this medication.

Side Effects

Common Side Effects:

• Stomach pain
• Heartburn
• Nausea
• Diarrhea
• Dizziness
• Headache

Serious Side Effects:

• Severe stomach pain or vomiting
• Black or bloody stools
• Unusual weight gain or swelling
• Shortness of breath
• Severe allergic reactions (rash, itching, swelling of the face/tongue/throat)

Precautions

• Inform your doctor of any existing health conditions, especially gastrointestinal, liver, or kidney diseases.
• Use the lowest effective dose for the shortest duration possible to reduce the risk of side effects.
• Ensure regular monitoring of blood pressure and kidney function during long-term use.

Storage Instructions

• Store Ponstan capsules at room temperature between 68°F and 77°F (20°C and 25°C).
• Keep the medication in its original container, tightly closed, and away from moisture and light.
• Do not store it in the bathroom to avoid exposure to humidity.
• Keep out of reach of children and pets.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/015034s045lbl.pdf