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Pamelor (nortriptyline)

Indications

• Used primarily to treat symptoms of depression, helping to improve mood and sense of well-being.
• Effective in managing certain types of chronic pain, providing relief by altering pain perception.
• It helps to alleviate symptoms of anxiety, promoting a calmer state of mind.
• Sometimes prescribed to prevent migraines and reduce the frequency and severity of headaches.

Dosage and Administration

• Take the capsule exactly as prescribed by your doctor.
• Swallow the capsule whole with a full glass of water.
• Take the medication at the same time each day to maintain consistent blood levels.
• Take the missed dose as soon as you remember unless it’s close to the time for your next dose. In that case, skip the missed dose.
• Inform your doctor of all medications you are currently taking to avoid interactions.
• Do not crush, chew, or open the capsules.
• Do not abruptly stop taking the medication without consulting your doctor.
• Do not consume alcohol while taking this medication, as it can increase side effects.
• Do not drive or operate heavy machinery until you know how the medication affects you.
• Do not take more than the prescribed dose.

Mechanism of Action

Pamelor (Nortriptyline) is a tricyclic antidepressant. It works by increasing the levels of certain natural substances in the brain, such as norepinephrine and serotonin, which help to maintain mental balance and improve mood.

Contraindications

• Recent Heart Attack: Do not use the medication if you have had a recent heart attack, as it may worsen your condition.
• Allergic Reaction: Avoid if you are allergic to Nortriptyline or any other ingredient in the capsule.
• MAOI Use: Do not take this medication if you are currently using or have recently used a monoamine oxidase inhibitor (MAOI) within the last 14 days.
• Severe Liver Disease: Not recommended for use if you have severe liver disease, as it can exacerbate the condition.

Side Effects

Common Side Effects:

• Drowsiness
• Dry mouth
• Dizziness
• Constipation
• Blurred vision
• Weight gain

Serious Side Effects:

• Irregular heartbeats
• Severe mood changes
• Seizures
• Difficulty urinating
• Severe allergic reactions (rash, itching, swelling)
• Suicidal thoughts

Precautions

• Monitor for Mood Changes: Watch for any changes in mood, behavior, or thoughts of self-harm and report them to your doctor immediately.
• Inform about Medical History: Let your doctor know if you have a history of heart problems, glaucoma, seizures, or thyroid issues.
• Pregnancy and Breastfeeding: Discuss with your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
• Avoid Sudden Position Changes: Stand up slowly from sitting or lying positions to prevent dizziness and falls.
• Regular Check-ups: Attend all scheduled appointments to monitor your progress and any side effects.

Storage Instructions

• Keep the capsules at a temperature between 68°F and 77°F (20°C to 25°C).
• Store in a dry place away from excessive heat and moisture, such as the bathroom.
• Ensure the medication is stored securely away from children and pets.
• Dispose of unused or expired medication properly, following local regulations or pharmacy guidelines.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/018012s029,018013s061lbl.pdf