Are you Looking to Buy Oxsoralen (Methoxsalen) from PrescriptionPoint.

Oxsoralen (methoxsalen)

Indications

• Psoriasis: Oxsoralen capsules are prescribed for the treatment of severe psoriasis, particularly when other treatments have not been effective. The medication is typically used in conjunction with ultraviolet A (UVA) light therapy.
• Vitiligo: Oxsoralen is also used to treat vitiligo, a condition that causes loss of skin color in patches, by helping to repigment the skin.
• Cutaneous T-Cell Lymphoma (CTCL): It is sometimes prescribed as part of PUVA therapy (psoralen plus UVA) for patients with CTCL, a type of skin lymphoma.

Ingredients

• Active Ingredient: Methoxsalen (8-Methoxypsoralen)
• Inactive Ingredients: Lactose, magnesium stearate, gelatin (capsule shell)

Dosage and Administration

• Take Oxsoralen capsules as prescribed, usually 2-4 hours before exposure to UVA light. The exact timing should be determined by your healthcare provider.
• Swallow the capsules whole with a full glass of milk or low-fat food to minimize stomach upset.
• Follow your healthcare provider’s instructions regarding the duration and frequency of light therapy sessions.
• Wear UVA-blocking sunglasses and protective clothing for at least 8 hours after taking Oxsoralen to prevent accidental exposure to sunlight.
• Inform your doctor of any other medications or supplements you are taking to avoid potential interactions.
• Do not take Oxsoralen capsules without access to UVA light therapy, as the medication alone can increase the risk of skin damage and cancer.
• Avoid excessive sunlight exposure or artificial UV light sources after taking Oxsoralen, as this can lead to severe sunburn or skin damage.
• Do not take more than the prescribed dose, as overexposure to UVA light in combination with Oxsoralen can increase the risk of serious side effects.
• Avoid tanning beds or other sources of UVA light outside of your prescribed treatment regimen.

Mechanism of Action

Oxsoralen contains methoxsalen, a photosensitizing agent that increases the skin’s sensitivity to UVA light. When taken orally, methoxsalen is absorbed into the bloodstream and reaches the skin, where it intercalates into DNA. Upon exposure to UVA light, methoxsalen binds to DNA and forms crosslinks, which can help slow down the rapid cell turnover associated with conditions like psoriasis. In vitiligo, it helps stimulate melanocyte activity, promoting repigmentation of the skin.

Contraindications

• Sensitivity to Methoxsalen: Do not use Oxsoralen if you have a history of sensitivity to methoxsalen or any of the other ingredients in the capsules.
• Skin Cancer: Avoid use if you have a history of skin cancer.
• Lupus and Porphyria: Do not use if you have lupus, porphyria, or other conditions that increase sensitivity to light.

Side Effects

Common Side Effects:

• Nausea or upset stomach
• Dizziness
• Headache
• Mild skin redness or itching following UVA exposure

Serious Side Effects:

• Severe skin blistering or peeling
• Persistent sunburn-like symptoms
• Eye pain or visual disturbances
• Darkening of the skin (hyperpigmentation)
• Increased risk of skin cancer with prolonged use

Precautions

• Always wear UVA-blocking sunglasses outdoors for at least 24 hours after taking Oxsoralen, even on cloudy days, to protect your eyes from damage.
• Use sunscreen with a high SPF on all exposed skin and wear protective clothing during the treatment period and for several days after.
• If you experience severe skin reactions or signs of an allergic reaction, such as hives, difficulty breathing, or swelling of the face or throat, seek immediate medical attention.

Storage Instructions

• Store Oxsoralen capsules at room temperature, between 59°F and 77°F (15°C and 25°C).
• Keep the capsules in their original packaging to protect them from light and moisture.
• Ensure the medication is stored out of reach of children and pets to prevent accidental ingestion.

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Prescription Requirement: We prioritize your well-being by requiring a valid prescription from a healthcare provider, ensuring that Oxsoralen is suitable for your condition.

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Generic Alternatives: Besides the brand-name Oxsoralen, we offer generic Methoxsalen, which is just as effective and more budget friendly.

Customer Service

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How to Order Oxsoralen Online in Canada?

Online

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Phone

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References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2003/09048slr037_methoxsalen_lbl.pdf