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Formulation : Tablet
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Dosage: 5mg
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Onglyza (Saxagliptin)

Indications

  • Onglyza is indicated for the treatment of type 2 diabetes mellitus in adults.
  • Used to improve blood sugar control in conjunction with diet and exercise.

Dosage and Administration

  • Take Onglyza exactly as prescribed by your doctor, typically once daily.
  • Swallow the tablet whole with a glass of water, with or without food.
  • Maintain a consistent routine, taking Onglyza at the same time each day.
  • Monitor your blood sugar levels regularly as directed by your doctor.
  • Follow your doctor’s recommendations on diet and exercise to achieve optimal blood sugar control.
  • Do not skip doses or stop taking Onglyza without consulting your doctor, as this can affect your blood sugar control.
  • Avoid consuming excessive amounts of alcohol, as it can increase the risk of low blood sugar.
  • Do not crush, chew, or break the tablet; swallow it whole.
  • Avoid using Onglyza if you have a history of serious allergic reactions to saxagliptin or any of its components.

Mechanism of Action

Onglyza contains saxagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor. It works by increasing the levels of incretin hormones, which help regulate blood sugar by increasing insulin release and decreasing glucagon production in response to meals. This helps to lower blood sugar levels in people with type 2 diabetes.

Contraindications

  • Do not use Onglyza if you have a known allergy to saxagliptin or any of the other ingredients in the tablet.
  • Avoid using Onglyza if you have a history of pancreatitis or severe kidney problems without consulting your doctor.

Side Effects

Common Side Effects

  • Upper respiratory tract infections
  • Urinary tract infections
  • Headache
  • Sinusitis
  • Diarrhea

Serious Side Effects

  • Severe allergic reactions (rash, itching, swelling, difficulty breathing)
  • Pancreatitis (severe abdominal pain, nausea, vomiting)
  • Heart failure (shortness of breath, swelling of the ankles/feet, unusual tiredness)
  • Low blood sugar (sweating, dizziness, shaking, hunger, confusion)

Precautions

  • Inform your doctor about any existing medical conditions, especially kidney problems, heart failure, or a history of pancreatitis.
  • Be cautious if you are pregnant, planning to become pregnant, or breastfeeding; discuss the risks and benefits with your healthcare provider.
  • Regularly monitor your blood sugar levels and report any significant changes to your doctor.
  • Watch for signs of low blood sugar, especially if you are taking other medications that can lower blood sugar.
  • Inform your healthcare provider about all medications, including over-the-counter drugs and supplements, to avoid potential interactions.

Storage Instructions

  • Store Onglyza tablets at room temperature (15°C to 30°C) in a dry place, away from moisture and heat.
  • Keep the bottle tightly closed when not in use.
  • Do not use Onglyza if the tablets show signs of discoloration or damage.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/022350s014lbl.pdf

Additional information

Brand Name:

Onglyza

Scientific Name:

Saxagliptin

Other Names:

Onglyza, Saxagliptin

Strength(s):

2.5mg, 5mg

Quantities Available:

28, 30, 84, 90, 112

Formulation:

Tablet

The information above is provided by third parties to Prescriptionpoint.com for Onglyza (Saxagliptin). This information is for general purposes only and is not intended to replace a physician's advice. Always consult with your doctor or a qualified health care professional if you need advice on any medical concerns.


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