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Minipress (prazosin)

Indications

• Minipress tablets are primarily prescribed for the management of high blood pressure (hypertension), helping to lower blood pressure and reduce the risk of heart-related complications.
• It may also be used to improve urination in men with benign prostatic hyperplasia (BPH), a condition characterized by enlargement of the prostate gland.

Dosage and Administration

• Take Minipress exactly as directed by your healthcare provider, typically once or twice daily.
• Take it regularly to maintain a consistent level of medication in your body.
• Take Minipress with or without food but taking it with food can help reduce stomach upset.
• Do not skip doses of Minipress.
• Avoid abruptly stopping Minipress without consulting your doctor, as this may lead to rebound hypertension or other adverse effects.

Mechanism of Action

Minipress tablets work by relaxing and widening the blood vessels, allowing blood to flow more easily. This helps to lower blood pressure by reducing the resistance against which the heart pumps, as well as improving urinary symptoms associated with benign prostatic hyperplasia.

Contraindications

• Allergic Reaction: Do not take Minipress if you have a known allergy to Prazosin or any other ingredients in the medication.
• Low Blood Pressure: It is contraindicated in patients with hypotension (low blood pressure) or those prone to orthostatic hypotension (a sudden drop in blood pressure upon standing).
• History of Syncope: Avoid Minipress if you have a history of syncope (fainting) or severe dizziness.

Side Effects

Common Side Effects:

• Dizziness
• Headache
• Fatigue

Serious Side Effects:

• Fainting
• Irregular heartbeat
• Swelling of the extremities

Precautions

• First Dose Effect: Be cautious when taking the first dose of Minipress, as it may cause a sudden drop in blood pressure leading to dizziness or fainting.
• Avoid Driving: Minipress may cause dizziness or drowsiness, so avoid driving or operating heavy machinery until you know how the medication affects you.
• Rise Slowly: To minimize the risk of orthostatic hypotension, rise slowly from a sitting or lying position, especially in the morning or after prolonged periods of rest.

Storage Instructions

• Store Minipress at room temperature away from moisture and heat.
• Keep the medication in its original container with the lid tightly closed to protect it from air and moisture.
• Store out of reach of children and pets to prevent accidental ingestion.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/017442s033lbl.pdf