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Lotemax (loteprednol etabonate)

Indications

• Lotemax is used to treat inflammation and pain following eye surgery.
• It is prescribed for the treatment of allergic conjunctivitis, which causes redness, itching, and swelling of the eyes.
• Lotemax helps manage inflammation of the uvea (the middle layer of the eye) in conditions like uveitis.
• It is used to treat various forms of eye inflammation that do not involve bacterial or viral infections.

Dosage and Administration

• Use Lotemax exactly as prescribed by your healthcare provider.
• Shake the bottle well before each use to ensure the medication is properly mixed.
• Tilt your head back and pull down the lower eyelid to create a small pocket before applying the drops.
• Place the dropper above the eye, squeeze out the prescribed number of drops, and close your eye for a minute or two.
• Use the drops at the same times each day to maintain consistent levels of the medication in your eye.
• Avoid touching the dropper tip to any surface, including your eye or hands, to prevent contamination.
• Do not use more than the prescribed dose, as overuse can increase the risk of side effects.
• Do not wear contact lenses while using Lotemax unless your doctor advises otherwise.

Mechanism of Action

Lotemax (loteprednol etabonate) is a corticosteroid that works by reducing inflammation and immune responses in the eye. It inhibits the release of substances in the body that cause inflammation, such as prostaglandins and leukotrienes. This helps to decrease symptoms like redness, swelling, and irritation.

Contraindications

• Viral, Fungal, or Tubercular Eye Infections: Do not use the eye drops if you have an eye infection caused by viruses (such as herpes simplex), fungi, or tuberculosis.
• Allergy to Loteprednol: Do not use it if you have a known allergy to Loteprednol or any other ingredients in the drops.
• Untreated Pus-Producing Eye Infections: Avoid use in untreated bacterial eye infections producing pus.

Side Effects

Common Side Effects:

• Temporary blurred vision
• Mild eye irritation or discomfort
• Dry eyes
• Watery eyes
• Headache

Serious Side Effects:

• Eye pain
• Vision changes
• Increased eye pressure (glaucoma)
• Eye infection signs (redness, swelling, discharge)
• Severe eye irritation or swelling
• Allergic reactions (rash, itching, swelling, severe dizziness, trouble breathing)

Precautions

• Regular Eye Exams: Have regular eye examinations to monitor for increased eye pressure or other potential side effects.
• Inform About Other Medications: Tell your doctor about all other eye medications you are using to avoid potential interactions.
• Pregnancy and Breastfeeding: Discuss with your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
• Prolonged Use: Avoid long-term use of Lotemax unless specifically directed by your doctor, as it can increase the risk of side effects.
• Signs of Infection: Contact your doctor immediately if you develop signs of an eye infection.

Storage Instructions

• Store Lotemax at room temperature between 15°C to 25°C (59°F to 77°F).
• Store in a dry place, away from moisture and light.
• Do not freeze the medication.
• Keep the drops in their original container with the cap tightly closed when not in use.
• Ensure the medication is stored safely away from children.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/202872lbl.pdf