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Entocort Enema (Budesonide)

Indications

Entocort Enema is prescribed for the treatment of mild to moderate active ulcerative colitis involving the rectum and the sigmoid colon. It helps reduce inflammation and symptoms such as pain and diarrhea.

Ingredients

• Active Ingredient: Budesonide
• Inactive Ingredients: Disodium edetate, Citric acid, Polysorbate 80, Sodium chloride, Sodium citrate, Sorbitol, Water for injection

Dosage and Administration

• Use Entocort Enema exactly as prescribed by your healthcare provider.
• Administer the enema once daily at bedtime, as this allows the medication to work overnight.
• Shake the enema bottle well before use to ensure proper mixing of the medication.
• Lie on your left side with your left leg straight and your right knee bent for easier administration.
• Hold the enema bottle firmly, insert the applicator tip into the rectum, and gently squeeze the bottle to release the medication.
• Remain lying down for at least 30 minutes to allow the medication to spread evenly and maximize absorption.
• Do not use the enema if the solution is discolored or contains particles.
• Avoid using more than the recommended dose to prevent adverse effects.
• Do not discontinue use abruptly without consulting your doctor, as this may lead to a flare-up of symptoms.
• Do not use the enema if you have a systemic infection, unless directed by your doctor.
• Avoid using the enema if you have severe hepatic impairment without consulting your healthcare provider.

Mechanism of Action

Entocort Enema contains budesonide, a potent corticosteroid. It works by inhibiting the release of inflammatory substances in the body. This helps to reduce inflammation and alleviate symptoms such as pain, swelling, and diarrhea associated with ulcerative colitis. Budesonide has a high topical anti-inflammatory effect in the gut with minimal systemic side effects due to its extensive first-pass metabolism.

Contraindications

• Do not use Entocort Enema if you are allergic to budesonide or any of the inactive ingredients.
• Avoid use if you have untreated bacterial, fungal, or viral infections.
• Do not use it if you have a known hypersensitivity to corticosteroids.
• Consult your doctor if you have a history of severe liver disease or systemic infections.

Side Effects

Common Side Effects:

• Mild abdominal pain
• Nausea
• Headache
• Dizziness
• Tiredness

Serious Side Effects:

• Severe allergic reactions (e.g., rash, itching, swelling of the face or throat, difficulty breathing)
• Worsening of symptoms
• Rectal bleeding
• Signs of infection (e.g., fever, chills)
• Adrenal suppression

Precautions

• Inform your doctor about all medications, supplements, and herbal products you are taking to avoid potential interactions.
• Use Entocort Enema with caution if you have a history of infections, liver disease, or adrenal gland problems.
• Regularly monitor your condition and inform your doctor of any changes or worsening of symptoms.
• Follow your doctor’s recommendations regarding diet and lifestyle modifications to manage ulcerative colitis.
• Do not stop using the enema without consulting your healthcare provider, even if you feel better.

Storage Instructions

• Store Entocort Enema at room temperature, between 15°C to 25°C (59°F to 77°F).
• Keep the enema bottle tightly closed when not in use.
• Protect from light and moisture.
• Do not refrigerate or freeze.
• Keep out of reach of children and pets.

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How to Order Entocort Enema Online in Canada?

Online

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Phone

For personalized assistance, you can place your order for Entocort Enema by speaking with one of our friendly customer support representatives. Just call us on +1-877-244-0431, and we will be happy to assist you.

Fax

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References

https://pdf.hres.ca/dpd_pm/00044077.PDF