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Cortenema (hydrocortisone enema)

Indications

Cortenema is prescribed for the treatment of ulcerative colitis, a condition that causes inflammation and sores in the lining of the colon and rectum.

Ingredients

  • Active Ingredient: Hydrocortisone
  • Inactive Ingredients: Benzyl alcohol, edetate disodium, polysorbate 80, propylene glycol, purified water, sodium hydroxide, and methylcellulose.

Dosage and Administration

  • Follow the prescription: Use Cortenema exactly as prescribed by your healthcare provider.
  • Administer at bedtime: Apply the enema at bedtime for optimal effectiveness and retention.
  • Shake well: Shake the enema bottle well before use to ensure the medication is evenly distributed.
  • Lie on left side: Lie on your left side with your left leg extended and your right leg bent for easier administration.
  • Retain enema: Try to retain the enema for at least 30 minutes, preferably overnight.
  • Do not skip doses: Consistency is crucial for the effectiveness of the treatment; do not skip doses.
  • Avoid sudden discontinuation: Do not suddenly stop using Cortenema without consulting your doctor, as it can worsen your condition.
  • Do not use it with rectal conditions: Avoid using it if you have rectal abscess, perforation, or recent bowel surgery.

Mechanism of Action

Hydrocortisone is a corticosteroid that works by reducing inflammation and suppressing the immune response in the colon. It helps to decrease symptoms such as swelling, pain, and irritation caused by ulcerative colitis.

Contraindications

  • Allergy to hydrocortisone: Do not use it if you are allergic to hydrocortisone or any other ingredients in Cortenema.
  • Systemic fungal infections: Avoid if you have systemic fungal infections.
  • Severe infections: Do not use it if you have untreated bacterial, viral, or parasitic infections.

Side Effects

Common Side Effects

  • Rectal pain or burning
  • Increased appetite
  • Weight gain
  • Mood changes
  • Trouble sleeping
  • Increased sweating

Serious Side Effects

  • Severe allergic reactions (rash, itching, swelling, severe dizziness, trouble breathing)
  • Signs of infection (fever, persistent sore throat)
  • Vision problems
  • Severe stomach/abdominal pain
  • Black or tarry stools
  • Unusual bleeding or bruising

Precautions

  • Medical history: Inform your doctor of your complete medical history, especially if you have diabetes, high blood pressure, liver disease, or gastrointestinal issues.
  • Monitor for side effects: Be aware of potential side effects and seek medical attention if serious symptoms occur.
  • Avoid exposure to infections: Avoid contact with people who have infections, as corticosteroids can weaken your immune system.
  • Monitor blood sugar levels: If you have diabetes, monitor your blood sugar levels closely as corticosteroids can affect glucose levels.
  • Pregnancy and breastfeeding: Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Storage Instructions

  • Store at room temperature: Keep Cortenema at a controlled room temperature, between 20°C to 25°C (68°F to 77°F).
  • Avoid moisture and light: Store in a dry place away from light and moisture.
  • Keep out of reach of children: Ensure that the medication is stored safely out of reach of children and pets.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/016199s035lbl.pdf

Additional information

Brand Name:

Cortenema

Scientific Name:

Hydrocortisone Enema

Other Names:

Cortenema

Strength(s):

100mg

Quantities Available:

420mL

Formulation:

Enema

The information above is provided by third parties to Prescriptionpoint.com for Cortenema (Hydrocortisone Enema). This information is for general purposes only and is not intended to replace a physician's advice. Always consult with your doctor or a qualified health care professional if you need advice on any medical concerns.


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