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Clinoril (sulindac)

Indications

• Clinoril tablets are prescribed to you for the relief of pain, swelling, and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
• This medication helps to improve mobility and reduce joint stiffness caused by these inflammatory conditions.

Dosage and Administration

• Take Clinoril tablets orally with a full glass of water, usually once or twice daily, or as directed by your healthcare provider.
• Swallow the tablets whole to avoid stomach irritation.
• Do not crush, chew, or break the tablets before swallowing.
• Avoid taking more than the prescribed dose or using it for longer than recommended.

Mechanism of Action

Clinoril belongs to a class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). It works by inhibiting the production of prostaglandins, substances in the body that cause inflammation, pain, and fever.

Contraindications

• Do not use Clinoril if you have a history of allergic reactions to sulindac or other NSAIDs, such as aspirin or ibuprofen.
• Avoid using this medication if you have a history of gastrointestinal bleeding, peptic ulcer disease, or kidney problems.
• Inform your doctor about any allergies you have to medications or if you are pregnant or breastfeeding.

Side Effects

Common side effects:

• Stomach upset or pain
• Nausea or vomiting
• Diarrhea or constipation
• Headache
• Dizziness

Serious side effects:

• Allergic reactions such as rash, itching, swelling of the face or throat, or difficulty breathing
• Gastrointestinal bleeding or ulcers
• Kidney problems or fluid retention

Precautions

• Before using Clinoril, inform your healthcare provider about your medical history, especially if you have a history of heart disease, high blood pressure, or liver problems.
• Avoid alcohol consumption while taking Clinoril, as it may increase the risk of stomach bleeding or liver damage.
• Regularly monitor your blood pressure and kidney function while using this medication, especially if you are taking it long-term.

Storage Instructions

• Store Clinoril tablets at room temperature away from moisture and heat.
• Keep the tablets in their original container and out of reach of children.
• Do not store Clinoril in the bathroom.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/017911s073lbl.pdf