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Carnitor (levocarnitine)

Indications

• Carnitor tablets are indicated for the treatment of carnitine deficiency in patients with certain genetic disorders or in those undergoing hemodialysis.
• It is also used as a nutritional supplement for patients with primary and secondary carnitine deficiencies.

Dosage and Administration

• Take Carnitor tablets exactly as prescribed by your doctor, usually one to three times daily.
• Swallow the tablets whole with a full glass of water.
• Follow your doctor’s instructions regarding the appropriate dosage and frequency of Carnitor use.
• Take a missed dose as soon as you remember unless it is almost time for the next dose. In that case, skip the missed dose and resume your regular dosing schedule.
• Do not exceed the prescribed dose of Carnitor or take it more frequently than directed by your doctor.
• Avoid consuming Levocarnitine-containing foods or supplements while taking Carnitor, as it may lead to excessive intake.
• Do not crush, chew, or break the medicine.
• Do not stop taking Carnitor abruptly without consulting your doctor, as it may worsen your condition.

Mechanism of Action

Carnitor contains Levocarnitine, a naturally occurring substance in the body that plays a vital role in energy production. Levocarnitine helps transport long-chain fatty acids into the mitochondria, where they are metabolized to produce energy.

Contraindications

• Do not use Carnitor if you have a known allergy to Levocarnitine or any other ingredients in the tablets.
• Avoid Carnitor if you have primary systemic carnitine deficiency, secondary carnitine deficiency due to hemodialysis, or trimethylaminuria (fish odor syndrome).
• Consult your doctor before using Carnitor if you have kidney disease, liver disease, or a history of seizures.

Side Effects

Common Side Effects:

• Nausea or vomiting
• Diarrhea
• Stomach cramps
• Body odor
• Muscle weakness

Serious Side Effects:

• Allergic reactions (rash, itching, swelling, difficulty breathing)
• Seizures
• Changes in mood or behavior
• Irregular heartbeat
• Signs of dehydration (excessive thirst, dry mouth, decreased urine output)

Precautions

• Inform your doctor about any existing medical conditions or medications you are taking before using Carnitor.
• Be cautious when driving or operating machinery until you know how Carnitor affects you, as it may cause dizziness or drowsiness.
• Monitor for signs of muscle weakness or changes in mental status while taking Carnitor, especially in patients with renal impairment.
• If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of Carnitor with your healthcare provider.

Storage Instructions

• Store Carnitor tablets at room temperature (20°C to 25°C) in a dry place, away from moisture and heat.
• Keep the tablets in their original packaging until they are ready to use.
• Do not use Carnitor if the tablets appear discolored, damaged, or show signs of deterioration.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/018948s024,019257s011lbl.pdf