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Cardizem CD (diltiazem)

Indications

• Cardizem CD prolonged-release capsules are indicated for the treatment of hypertension (high blood pressure) to lower blood pressure and reduce the risk of cardiovascular events such as heart attacks and strokes.
• It is also used for the management of chronic stable angina (chest pain) and certain types of irregular heart rhythms (arrhythmias).

Dosage and Administration

• Take Cardizem CD exactly as prescribed by your doctor, usually once daily.
• Swallow the capsules whole with a full glass of water.
• Take Cardizem CD at the same time each day to maintain a consistent level of medication in your body.
• Follow your doctor’s instructions regarding diet and exercise while taking Cardizem CD.
• Do not exceed the prescribed dose of Cardizem CD or take it more frequently than directed by your doctor.
• Do not crush, chew, or break them.
• Avoid consuming grapefruit or grapefruit juice while taking Cardizem CD, as it can increase the medication’s levels in your blood.
• Do not stop taking Cardizem CD abruptly without consulting your doctor, as it may worsen your condition.

Mechanism of Action

Cardizem CD contains Diltiazem, a calcium channel blocker. It works by relaxing the muscles of your blood vessels and heart, which helps to lower blood pressure, improve blood flow, and reduce the workload on the heart.

Contraindications

• Do not use Cardizem CD if you have a known allergy to Diltiazem or any other ingredients in the capsules.
• Avoid Cardizem CD if you have certain types of heart rhythm disorders (sick sinus syndrome, second- or third-degree atrioventricular block) or severe low blood pressure.
• Consult your doctor before using Cardizem CD if you have severe liver disease or heart failure.

Side Effects

Common Side Effects:

• Dizziness or lightheadedness
• Headache
• Flushing
• Swelling of the ankles or feet
• Constipation or diarrhea

Serious Side Effects:

• Slow or irregular heartbeat
• Shortness of breath
• Fainting
• Severe allergic reactions (rash, itching, swelling, difficulty breathing)
• Signs of liver problems (yellowing of the skin or eyes, dark urine, abdominal pain)

Precautions

• Inform your doctor about any existing medical conditions or medications you are taking before using Cardizem CD.
• Be cautious when driving or operating machinery until you know how Cardizem CD affects you, as it may cause dizziness or drowsiness.
• Monitor for signs of heart failure, such as swelling of the ankles or feet and shortness of breath, and report these symptoms to your doctor.
• If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of Cardizem CD with your healthcare provider.

Storage Instructions

• Store Cardizem capsules at room temperature (20°C to 25°C) in a dry place, away from moisture and heat.
• Keep the capsules in their original packaging until ready to use.
• Do not use Cardizem CD if the capsules appear discolored, damaged, or show signs of deterioration.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/020062s046lbl.pdf