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Capoten (captopril)

Indications

• Capoten tablets are indicated for the treatment of hypertension (high blood pressure) to lower blood pressure and reduce the risk of cardiovascular events such as heart attacks and strokes.
• It is also used for the management of heart failure, to improve survival after a heart attack, and to treat diabetic nephropathy (kidney disease in diabetic patients).

Dosage and Administration

• Take Capoten tablets exactly as prescribed by your doctor, usually two to three times daily.
• Take the tablets on an empty stomach, one hour before meals.
• Follow your doctor’s instructions regarding diet and salt intake while taking Capoten.
• Monitor your blood pressure regularly to ensure the medication is working effectively.
• Drink plenty of fluids unless your doctor advises you to restrict fluid intake.
• Do not exceed the prescribed dose of Capoten or take it more frequently than directed by your doctor.
• Avoid consuming high-potassium foods or salt substitutes containing potassium while taking Capoten.
• Do not discontinue Capoten suddenly without consulting your doctor, as it may worsen your condition.

Mechanism of Action

Capoten contains Captopril, an angiotensin-converting enzyme (ACE) inhibitor. It works by blocking the formation of angiotensin II, a substance that narrows blood vessels. This relaxation of blood vessels helps to lower blood pressure, reduce the workload on the heart, and improve blood flow.

Contraindications

• Do not use Capoten if you have a known allergy to Captopril or any other ingredients in the tablets.
• Avoid Capoten if you have a history of angioedema (swelling of the face, lips, tongue, or throat) related to previous ACE inhibitor therapy.
• Consult your doctor before using Capoten if you have kidney disease, liver disease, or a history of blood disorders.

Side Effects

Common Side Effects:

• Cough
• Dizziness or lightheadedness
• Taste changes
• Rash
• Elevated blood potassium levels

Serious Side Effects:

• Severe allergic reactions (rash, itching, swelling, difficulty breathing)
• Angioedema (swelling of the face, lips, tongue, or throat)
• Severe hypotension (very low blood pressure)
• Kidney problems (changes in the amount of urine, swelling of ankles/feet)
• High potassium levels (muscle weakness, slow or irregular heartbeat)

Precautions

• Inform your doctor about any existing medical conditions, especially kidney or liver problems, before starting treatment with Capoten.
• Be cautious when standing up from a sitting or lying position to avoid dizziness or fainting.
• Monitor your blood pressure regularly and report any significant changes to your doctor.
• If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of Capoten with your healthcare provider.
• Avoid drinking alcohol while taking Capoten, as it can increase the risk of side effects such as dizziness or drowsiness.

Storage Instructions

• Store Capoten tablets at room temperature (20°C to 25°C) in a dry place, away from moisture and heat.
• Keep the tablets in their original packaging until they are ready to use.
• Do not use Capoten if the tablets appear discolored, damaged, or show signs of deterioration.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/018343s084lbl.pdf