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Benicar HCTZ (olmesartan/hctz)

Indications

Benicar HCT tablets are prescribed for:

  • Hypertension Management: Used to lower high blood pressure (hypertension), which helps prevent strokes, heart attacks, and kidney problems.
  • Combination Therapy: This medication is used when treatment with olmesartan alone or hydrochlorothiazide alone is not sufficient to control blood pressure.

Ingredients

  • Active Ingredients: Olmesartan medoxomil, hydrochlorothiazide.
  • Inactive Ingredients: Microcrystalline cellulose, lactose monohydrate, low-substituted hydroxypropyl cellulose, hydroxypropyl cellulose, magnesium stearate, titanium dioxide, talc, ferric oxide red (in some strengths), ferric oxide yellow (in some strengths).

Dosage and Administration

  • Take Benicar HCT tablets exactly as prescribed by your doctor, usually once daily with or without food.
  • Swallow the tablet whole with water; do not crush or chew it. If you miss a dose, take it as soon as you remember, but if it’s almost time for your next dose, skip the missed dose.
  • Regularly monitor your blood pressure to ensure the medication is effective.
  • Maintain adequate hydration but consult your doctor before making any significant changes to your fluid intake.
  • Do not stop taking Benicar HCT without consulting your doctor, even if you feel well, as hypertension often has no symptoms.
  • Avoid excessive intake of salt substitutes or potassium supplements while taking this medication, unless directed by your doctor.
  • Do not use this medication if you are pregnant, as it can cause harm to the fetus.

Mechanism of Action

Benicar HCT combines two antihypertensive agents: olmesartan medoxomil, an angiotensin II receptor blocker (ARB), and hydrochlorothiazide, a thiazide diuretic. Olmesartan works by blocking the action of angiotensin II, a substance in the body that causes blood vessels to tighten and narrow. By blocking this action, olmesartan helps relax blood vessels, lowering blood pressure. Hydrochlorothiazide works by helping the kidneys remove excess salt and water from the body, reducing fluid retention and further lowering blood pressure.

Contraindications

  • Do not use if you are allergic to olmesartan, hydrochlorothiazide, or any other ingredients in the tablet.
  • Contraindicated in patients with anuria (inability to urinate).
  • Not recommended for use during pregnancy due to the risk of fetal harm.
  • Avoid if you have a history of angioedema related to previous treatment with angiotensin receptor blockers (ARBs).

Side Effects

Common Side Effects:

  • Dizziness
  • Lightheadedness
  • Dehydration or dry mouth
  • Nausea or vomiting
  • Headache

Serious Side Effects:

  • Severe allergic reactions (rash, itching, swelling, severe dizziness, trouble breathing)
  • High potassium levels (muscle weakness, slow/irregular heartbeat)
  • Unusual tiredness or muscle cramps
  • Signs of kidney problems (change in the amount of urine)
  • Vision changes or eye pain (signs of glaucoma)

Precautions

  • Inform your doctor about any other medications you are taking, as Benicar HCT may interact with other drugs.
  • If you experience severe diarrhea or vomiting, contact your doctor immediately, as it may lead to dehydration and low blood pressure.
  • Use caution if you have a history of heart, kidney, or liver problems, as your condition may need to be closely monitored.
  • Notify your doctor if you experience any signs of electrolyte imbalance, such as muscle cramps, weakness, or confusion.
  • If you have a history of lupus, inform your doctor, as hydrochlorothiazide may cause your lupus symptoms to worsen.

Storage Instructions

  • Store Benicar HCT tablets at room temperature, between 68°F to 77°F (20°C to 25°C).
  • Keep the tablets in their original packaging, tightly closed, and protect them from moisture and light.
  • Do not store it in the bathroom, as humidity may affect the medication.
  • Keep out of reach of children and pets.

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References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/021532s037lbl.pdf

Additional information

Scientific Name:

Olmesartan/HCTZ, Olmesartan/Hctz, Olmesartan Medoxomil/Hctz

Formulation:

Film Coated Tablet, Tablet

Strength(s):

20/12.5mg, 20/25mg, 40/12.5mg, 40/25mg

Quantities Available:

28, 30, 84, 90, 100

The information above is provided by third parties to Prescriptionpoint.com for Benicar HCTZ (Olmesartan/Hctz). This information is for general purposes only and is not intended to replace a physician's advice. Always consult with your doctor or a qualified health care professional if you need advice on any medical concerns.


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