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Atacand (candesartan cilexetil)

Indications

• Atacand is used to treat high blood pressure (hypertension).
• It helps prevent strokes, heart attacks, and kidney problems by lowering blood pressure.
• Atacand is also used to treat heart failure and improve survival after a heart attack.

Dosage and Administration

• Take Atacand exactly as prescribed by your doctor, usually once daily.
• Swallow the tablets whole with a glass of water, with or without food.
• Take your doses at the same time each day to maintain consistent levels of the medication in your body.
• Inform your doctor about all other medications you are taking to avoid potential interactions.
• Do not take more than the prescribed dose.
• Avoid using Atacand if you are allergic to Candesartan or any of its ingredients.
• Do not stop taking Atacand abruptly without consulting your doctor.
• Avoid using potassium supplements or salt substitutes containing potassium without your doctor’s approval.
• Do not consume alcohol in excess while taking Atacand, as it can lower your blood pressure further and increase the risk of side effects.

Mechanism of Action

Atacand contains candesartan cilexetil, an angiotensin II receptor blocker (ARB). It works by blocking the action of angiotensin II, a substance in the body that causes blood vessels to tighten. By relaxing blood vessels, Atacand lowers blood pressure and improves blood flow, reducing the workload on the heart.

Contraindications

• Do not use Atacand if you are allergic to Candesartan or any of its ingredients.
• Avoid using Atacand if you are pregnant, planning to become pregnant, or breastfeeding, as it can harm the baby.
• Do not take Atacand if you have severe liver or kidney disease without consulting your doctor.
• Avoid using Atacand if you have a history of angioedema related to previous ARB or ACE inhibitor treatment.

Side Effects

Common Side Effects

• Dizziness
• Headache
• Fatigue
• Nausea
• Back pain

Serious Side Effects

• Severe allergic reactions, including rash, itching, swelling, severe dizziness, and trouble breathing
• Signs of high potassium levels, such as muscle weakness, slow or irregular heartbeat
• Signs of kidney problems, such as changes in urine output
• Severe abdominal pain
• Fainting or significant drop in blood pressure

Precautions

• Notify your doctor if you have a history of kidney disease, liver disease, heart problems, or electrolyte imbalances.
• Use caution if you are elderly, as you may be more sensitive to the effects of the medication.
• Stay hydrated, especially in hot weather, to avoid dehydration and low blood pressure.
• Monitor your blood pressure regularly and report any significant changes to your doctor.
• If you experience severe side effects or signs of an allergic reaction, seek medical attention immediately.

Storage Instructions

• Store Atacand at room temperature, between 20°C to 25°C (68°F to 77°F).
• Keep the tablets in their original container, tightly closed.
• Store Atacand out of reach of children and pets.
• Protect the tablets from moisture and light.
• Do not use Atacand after the expiration date on the package.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/020838s022lbl.pdf