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Arnuity Ellipta (fluticasone furoate)

Indications

• Long-term treatment to control and prevent asthma symptoms such as wheezing and shortness of breath.
• Helps in preventing asthma attacks and flare-ups in patients aged 5 years and older.

Dosage and Administration

• Use the inhaler once daily, at the same time each day.
• Use the inhaler exactly as directed by your healthcare provider.
• Rinse your mouth with water without swallowing after inhalation to prevent oral thrush.
• Keep track of the doses left in the inhaler to ensure timely refills.
• Take the missed dose as soon as possible unless it is almost time for the next dose.
• Do not use more than the prescribed dose.
• Do not double a dose.
• Do not take the inhaler apart or try to modify it.

Mechanism of Action

Arnuity Ellipta (fluticasone furoate) is an inhaled corticosteroid that reduces inflammation in the lungs. By decreasing inflammation, it helps to prevent and control asthma symptoms and improve breathing.

Contraindications

• Severe Allergy to Fluticasone: Do not use the medication if you are allergic to Fluticasone Furoate or any components of the inhaler.
• Primary Treatment of Status Asthmaticus: Not suitable for the relief of acute asthma attacks or status asthmaticus.
• Hypersensitivity: Avoid in patients with known hypersensitivity to milk proteins, as the inhaler may contain trace amounts.

Side Effects

Common Side Effects:

• Headache
• Throat irritation
• Hoarseness
• Cough
• Oral thrush (white patches in the mouth)
• Runny or stuffy nose

Serious Side Effects:

• Severe allergic reactions (rash, itching, swelling, severe dizziness, trouble breathing)
• Vision problems (blurred vision, eye pain)
• Increased wheezing or breathing difficulties
• Signs of infection (fever, persistent sore throat)
• Adrenal insufficiency (fatigue, muscle weakness, loss of appetite, weight loss)

Precautions

• Regular Monitoring: Have regular check-ups to monitor asthma control and lung function.
• Infection Risk: Increased risk of infections; avoid exposure to chickenpox or measles.
• Bone Health: Long-term use can affect bone density; ensure adequate calcium and vitamin D intake.
• Eye Health: Monitor for vision changes, as corticosteroids can increase the risk of cataracts and glaucoma.
• Growth in Children: Monitor growth regularly in children using this medication long-term.
• Interaction with Other Medications: Inform your doctor of all medications you are taking to avoid interactions.

Storage Instructions

• Store at room temperature, between 20°C to 25°C (68°F to 77°F).
• Store in a dry place away from moisture.
• Keep the inhaler in its original packaging until ready to use.
• Keep out of reach of children to prevent accidental use.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/205625s000lbl.pdf