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Alphagan Eyedrops (brimonidine)

Indications

• Alphagan Eyedrops is used to lower high eye pressure (intraocular pressure) in patients with open-angle glaucoma or ocular hypertension.
• It helps prevent further damage to the optic nerve and loss of vision caused by high eye pressure.

Dosage and Administration

• Use Alphagan Eyedrops exactly as prescribed by your doctor, typically one drop in the affected eye(s) three times daily.
• Wash your hands before using the eye drops to avoid contamination.
• Tilt your head back, look upward, and pull down the lower eyelid to create a small pocket before applying the drop.
• Close your eyes for 1-2 minutes after applying the drop to allow the medication to be absorbed.
• Wait at least 5 minutes before applying other drops if you use other eye drops as well.
• Do not touch the dropper tip on any surface, including your eye, to avoid contamination.
• Avoid using Alphagan Eyedrops if the solution changes color or becomes cloudy.
• Do not share your eye drops with others, even if they have similar symptoms.
• Avoid driving or operating heavy machinery until you know how Alphagan Eyedrops affect your vision, as it can cause temporary blurred vision or dizziness.
• Do not use Alphagan Eyedrops if you are allergic to brimonidine or any of its ingredients.

Mechanism of Action

Alphagan Eyedrops contain Brimonidine, an alpha-2 adrenergic agonist. It works by decreasing the amount of fluid produced in the eye and increasing the outflow of fluid from the eye. This dual action helps to lower intraocular pressure, reducing the risk of damage to the optic nerve and vision loss in patients with glaucoma or ocular hypertension.

Contraindications

• Do not use Alphagan Eyedrops if you are allergic to brimonidine or any of its ingredients.
• Avoid using the eye drops if you are taking monoamine oxidase inhibitors (MAOIs) or have taken them within the last 14 days.
• Do not use Alphagan Eyedrops if you have severe cardiovascular disease, such as a recent heart attack or stroke, without consulting your doctor.

Side Effects

Common Side Effects:

• Mild eye redness
• Itching or discomfort in the eyes
• Dry mouth
• Blurred vision
• Headache

Serious Side Effects:

• Severe allergic reactions, including rash, itching, swelling, severe dizziness, and trouble breathing
• Eye pain or swelling
• Vision changes
• Unusual tiredness or drowsiness
• Signs of a severe decrease in blood pressure, such as fainting or severe dizziness

Precautions

• Inform your doctor about all other medications you are using, including over-the-counter products and supplements.
• Notify your doctor if you have a history of heart disease, high blood pressure, depression, Raynaud’s disease, or blood circulation disorders.
• Use caution if you are pregnant, planning to become pregnant, or breastfeeding, and discuss the risks and benefits with your doctor.
• Avoid alcohol, as it can increase certain side effects of Alphagan Eyedrops.
• If you wear contact lenses, remove them before applying Alphagan Eyedrops and wait at least 15 minutes before reinserting them.
• If you experience severe side effects or signs of an allergic reaction, seek medical attention immediately.

Storage Instructions

• Store Alphagan Eyedrops at room temperature, between 15°C to 25°C (59°F to 77°F).
• Keep the bottle tightly closed when not in use.
• Store it out of reach of children and pets.
• Protect the eye drops from light and moisture.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020613s031lbl.pdf