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Formulation : Tablet
Drug Name Dosage Quantity Price Buy Now
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Actoplus Met
Dosage: 15/850mg
Quantity: 56
Price: $121.00
Actoplus Met
Dosage: 15/850mg
Quantity: 112
Price: $219.35

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Buy Generic Pioglitazone/Metformin

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Formulation : Tablet
Drug Name Dosage Quantity Price Buy Now
Pioglitazone/Metformin 15/850mg 90 $89.50 Add To Cart
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Pioglitazone/Metformin 15/850mg 180 $171.00 Add To Cart
Pioglitazone/Metformin
Dosage: 15/850mg
Quantity: 90
Price: $89.50
Pioglitazone/Metformin
Dosage: 15/500mg
Quantity: 100
Price: $52.00
Pioglitazone/Metformin
Dosage: 15/850mg
Quantity: 180
Price: $171.00

Actoplus Met (pioglitazone/metformin)

Indications

  • Actoplus Met Tablets are used for:
  • Managing Type 2 Diabetes: Actoplus Met is prescribed to help control high blood sugar levels in adults with type 2 diabetes. It is typically used when diet and exercise alone are not enough to manage blood glucose levels effectively.
  • Combination Therapy: This medication is often used in combination with other antidiabetic agents or insulin to improve blood sugar control.

Ingredients

  • Active Ingredients: Pioglitazone Hydrochloride, Metformin Hydrochloride.
  • Inactive Ingredients: Carnauba wax, hypromellose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, povidone, sodium starch glycolate, titanium dioxide, talc.

Dosage and Administration

  • Take Actoplus Met exactly as prescribed by your healthcare provider, usually once or twice daily with meals to reduce gastrointestinal side effects.
  • Swallow the tablets whole with a full glass of water, and do not crush or chew them.
  • Monitor your blood sugar levels regularly as advised by your doctor to ensure the medication is working effectively.
  • Maintain a consistent diet and exercise regimen alongside your medication to help manage your diabetes.
  • Do not skip doses or change your dosage without consulting your healthcare provider, as this can affect your blood sugar control.
  • Avoid consuming excessive alcohol while taking Actoplus Met, as it can increase the risk of lactic acidosis, a serious condition associated with metformin.
  • Do not take Actoplus Met if you have severe kidney disease, as metformin can accumulate and cause a serious condition called lactic acidosis.
  • Avoid using Actoplus Met if you have a history of heart failure or liver disease, unless your doctor has specifically prescribed it for you.

Mechanism of Action

  • Actoplus Met combines two medications: pioglitazone and metformin. Pioglitazone is a thiazolidinedione that increases the body’s sensitivity to insulin, helping cells use glucose more effectively. Metformin is a biguanide that works by decreasing glucose production in the liver and improving insulin sensitivity. Together, they help lower blood sugar levels in people with type 2 diabetes.

Contraindications

  • Do not use Actoplus Met if you are allergic to pioglitazone, metformin, or any other components of the medication.
  • Avoid this medication if you have severe kidney disease or are in a state of diabetic ketoacidosis.
  • Do not take Actoplus Met if you have active bladder cancer or a history of bladder cancer, as pioglitazone has been linked to an increased risk of bladder cancer.
  • Avoid using this medication if you have heart failure or severe liver problems, as it can exacerbate these conditions.

Side Effects

Common Side Effects:

  • Nausea
  • Diarrhea
  • Stomach pain
  • Weight gain
  • Upper respiratory tract infections
  • Headache

Serious Side Effects:

  • Lactic acidosis (symptoms include muscle pain, weakness, trouble breathing, slow or irregular heartbeat)
  • Heart failure (shortness of breath, swelling of the ankles or feet, sudden weight gain)
  • Bladder cancer (blood in the urine, painful urination, urinary urgency)
  • Hypoglycemia (dizziness, sweating, confusion, palpitations)
  • Liver problems (yellowing of the skin or eyes, dark urine, severe nausea)

Precautions

  • Inform your healthcare provider if you have a history of kidney, liver, or heart disease, as Actoplus Met may not be suitable for you.
  • Regularly monitor your blood sugar levels and kidney function while on Actoplus Met, especially if you are also taking other medications that affect kidney function.
  • Be cautious if you are undergoing surgery or any radiologic studies involving iodinated contrast materials, as metformin should be temporarily discontinued to reduce the risk of lactic acidosis.
  • Discuss with your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as Actoplus Met may not be recommended during pregnancy or breastfeeding.
  • If you experience symptoms of lactic acidosis (muscle pain, trouble breathing, unusual sleepiness), seek immediate medical attention.

Storage Instructions

  • Store Actoplus Met tablets at room temperature, between 68°F to 77°F (20°C to 25°C).
  • Keep the medication in its original container, tightly closed, and away from moisture, heat, and light.
  • Do not store in the bathroom or near a sink where it could be exposed to moisture.
  • Keep out of reach of children and pets to prevent accidental ingestion.

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References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021842s014s015lbl.pdf

Additional information

Brand Name:

Actoplus Met

Scientific Name:

Pioglitazone/Metformin

Other Names:

Competact, Dropia Met, Pioglit

Strength(s):

15/500mg, 15/850mg

Quantities Available:

56, 90, 100, 112, 180

Formulation:

Tablet

The information above is provided by third parties to Prescriptionpoint.com for Actoplus Met (Pioglitazone/Metformin). This information is for general purposes only and is not intended to replace a physician's advice. Always consult with your doctor or a qualified health care professional if you need advice on any medical concerns.


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