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Formulation : Tablet
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Diovan HCTZ (valsartan/hctz)

Indications

  • Diovan HCTZ tablets are used for:
  • Hypertension Management: Helps lower high blood pressure, reducing the risk of stroke, heart attack, and kidney problems.
  • Heart Failure Treatment: Assists in managing symptoms and improving heart function in patients with chronic heart failure.
  • Post-Heart Attack Therapy: Helps improve survival after a heart attack by easing the heart’s workload.

Ingredients

  • Active Ingredients: Valsartan, Hydrochlorothiazide
  • Inactive Ingredients: Microcrystalline cellulose, lactose monohydrate, magnesium stearate, colloidal silicon dioxide, crospovidone, hypromellose, titanium dioxide, talc, polyethylene glycol, red iron oxide (only for specific strengths)

Dosage and Administration

  • Take Diovan HCTZ tablets exactly as prescribed by your doctor, usually once daily.
  • Swallow the tablet whole with a glass of water.
  • Take the medication at the same time each day to maintain an even level in your blood.
  • You can take it with or without food but be consistent in the way you take it.
  • Regularly monitor your blood pressure and report any significant changes to your doctor.
  • Do not discontinue use without consulting your doctor, even if you feel well.
  • Avoid taking the medication if you are unable to urinate.

Mechanism of Action

Diovan HCTZ tablets combine two antihypertensive agents: valsartan and hydrochlorothiazide. Valsartan is an angiotensin II receptor blocker (ARB) that relaxes blood vessels, improving blood flow. Hydrochlorothiazide is a diuretic that helps eliminate excess salt and water from the body, reducing fluid retention and lowering blood pressure.

Contraindications

  • Do not use if you are allergic to valsartan, hydrochlorothiazide, or any other ingredients in Diovan HCTZ tablets.
  • Avoid use if you have severe kidney disease or are unable to urinate.
  • Do not use if you have a history of angioedema related to previous ACE inhibitor or ARB therapy.
  • Avoid if you have severe liver disease or cholestasis.
  • Consult your doctor if you have electrolyte imbalances, gout, or diabetes.

Side Effects

Common Side Effects

  • Dizziness
  • Lightheadedness
  • Dehydration
  • Headache
  • Fatigue
  • Cough

Serious Side Effects

  • Severe allergic reactions (e.g., rash, itching, swelling of the face or throat, difficulty breathing)
  • Signs of kidney problems (e.g., change in the amount of urine)
  • Severe dehydration or electrolyte imbalance (e.g., muscle cramps, weakness, irregular heartbeat)
  • Severe stomach or abdominal pain
  • Jaundice (yellowing of the skin or eyes)

Precautions

  • Inform your doctor about any other medications or supplements you are taking to avoid potential interactions.
  • Use with caution if you have a history of kidney or liver disease, electrolyte imbalances, or heart conditions.
  • Regularly monitor your electrolyte levels and kidney function as advised by your doctor.
  • Stay hydrated, especially in hot weather or to avoid dehydration.
  • Do not drive or perform activities requiring alertness until you know how the medication affects you.

Storage Instructions

  • Store Diovan HCTZ tablets at room temperature, between 20°C to 25°C (68°F to 77°F).
  • Keep the bottle tightly closed when not in use.
  • Protect from moisture and light.
  • Keep out of reach of children and pets.

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Generic Alternatives: Besides the brand-name Diovan HCTZ, we offer generic Valsartan and Hydrochlorothiazide, which is just as effective and more budget friendly.

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References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/020818s080lbl.pdf

Additional information

Brand Name:

Diovan HCTZ

Scientific Name:

Valsartan/Hctz, Valsartan/hctz

Other Names:

Co-Diovan, Diovan HCTZ, Valsartan HCT

Strength(s):

80/12.5mg, 160/12.5mg, 160/25mg, 320/12.5mg, 320/25mg

Quantities Available:

28, 30, 84, 90, 100

Formulation:

Tablet

The information above is provided by third parties to Prescriptionpoint.com for Diovan HCTZ (Valsartan/hctz). This information is for general purposes only and is not intended to replace a physician's advice. Always consult with your doctor or a qualified health care professional if you need advice on any medical concerns.


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