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Formulation : Capsule
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Sinequan (doxepin hydrochloride)

Indications

  • Sinequan is primarily prescribed to treat depression, alleviating symptoms such as persistent sadness, loss of interest in activities, and fatigue.
  • It is also effective in treating anxiety disorders, reducing symptoms like excessive worry, restlessness, and irritability.

Ingredients

  • Active Ingredient: Doxepin Hydrochloride
  • Inactive Ingredients: Corn starch, magnesium stearate, titanium dioxide, gelatin, sodium lauryl sulfate, and iron oxides (for color).

Dosage and Administration

  • Take Sinequan exactly as prescribed by your healthcare provider.
  • You can take the capsule with or without food, based on your preference or doctor’s advice.
  • Take the capsule at the same time each day to maintain a consistent level in your bloodstream.
  • Do not skip doses.
  • Do not stop taking Sinequan suddenly without consulting your doctor, as it may cause withdrawal symptoms.

Mechanism of Action

Sinequan (Doxepin) works by inhibiting the reuptake of certain neurotransmitters (serotonin and norepinephrine) in the brain, thereby enhancing their effects. This helps in improving mood and alleviating symptoms of depression and anxiety.

Contraindications

  • Do not use if you are allergic to Doxepin or any of the capsule’s ingredients.
  • Avoid using this medication if you have untreated narrow-angle glaucoma.
  • Do not take it if you have a history of severe urinary retention.
  • Avoid using Sinequan if you are currently taking or have recently taken monoamine oxidase inhibitors (MAOIs).

Side Effects

Common Side Effects

  • Dry mouth
  • Blurred vision
  • Dizziness
  • Drowsiness
  • Constipation
  • Weight gain

Serious Side Effects

  • Unusual thoughts or behavior
  • Severe dizziness or fainting
  • Severe abdominal pain
  • Mood changes such as agitation or confusion
  • Signs of an allergic reaction like rash, itching, or swelling
  • Yellowing of the skin or eyes (jaundice)

Precautions

  • Inform your doctor of your complete medical history.
  • Stay aware of any changes in mood, behavior, or thoughts of suicide, especially when starting Sinequan or changing dosage.
  • Limit alcohol as it can increase certain side effects, including dizziness.
  • Do not drive or operate heavy machinery until you know how Sinequan affects you.
  • Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Storage Instructions

  • Keep Sinequan at a controlled room temperature, between 20°C to 25°C (68°F to 77°F).
  • Store in a dry place away from light and moisture.
  • Keep out of reach of children.
  • Do not store it in the bathroom.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/016798s054,017516s023lbl.pdf

Additional information

Brand Name:

Sinequan

Scientific Name:

Doxepin, Doxepin Hydrochloride

Other Names:

Doxin, Sinequan

Strength(s):

10mg, 25mg, 50mg, 75mg, 100mg

Quantities Available:

100

Formulation:

Capsule

The information above is provided by third parties to Prescriptionpoint.com for Sinequan (Doxepin Hydrochloride). This information is for general purposes only and is not intended to replace a physician's advice. Always consult with your doctor or a qualified health care professional if you need advice on any medical concerns.


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