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Ceftin (cefuroxime) 

Indications

Ceftin tablets are indicated for the treatment of patients with mild to moderate infections, including: 

• Pharyngitis/tonsillitis 
• Acute bacterial exacerbations of chronic bronchitis 
• Acute bacterial sinusitis 
• Secondary bacterial infections of acute bronchitis 
• Uncomplicated skin and skin-structure infections 
• Uncomplicated urinary tract infections 
• Gonorrhea 
• Early Lyme disease (erythema migrans) 

Dosage and Administration

• Take Ceftin exactly as prescribed by your healthcare provider. 
• Swallow Ceftin tablets whole with a full glass of water. 
• Take Ceftin tablets with food to enhance absorption. 
• Complete the full course of treatment even if you start to feel better before finishing all your medication. 
• Do not crush or chew Ceftin tablets. 
• Do not skip doses or stop taking Ceftin without consulting your healthcare provider, as this may decrease the effectiveness of the treatment and increase the risk of bacterial resistance. 
• Do not share your medication with others, even if they have similar symptoms. 

Mechanism of Action

Ceftin is a cephalosporin antibiotic that works by interfering with the bacteria’s cell wall formation. This action causes the cell wall to rupture, resulting in the death of the bacteria. Ceftin is effective against a wide range of Gram-positive and Gram-negative bacteria. 

Contraindications

Ceftin are contraindicated in: 

• Patients with known allergy to the Cephalosporin group of antibiotics. 
• Patients with a history of severe hypersensitivity (e.g., anaphylaxis) to penicillins or other beta-lactam antibiotics. 

Side Effects

Common Side Effects: 

• Diarrhea 
• Nausea 
• Vomiting 
• Abdominal pain 
• Headache 
• Dizziness 
• Rash 

Serious Side Effects: 

• Severe allergic reactions (e.g., anaphylaxis, angioedema, severe skin reactions) 
• Clostridium difficile-associated diarrhea 
• Stevens-Johnson syndrome 
• Hepatic dysfunction (e.g., hepatitis, jaundice) 
• Hemolytic anemia 

Precautions

• Allergic Reactions: Inform your healthcare provider if you have a history of allergies to Penicillins, Cephalosporins, or other drugs. Discontinue use if a severe allergic reaction occurs.
• Diarrhea: Antibiotic-associated diarrhea can occur. If severe diarrhea occurs, contact your healthcare provider.
• Renal Impairment: Use Ceftin with caution if you have renal impairment. You may also need to adjust your doses.
• Superinfection: Prolonged use of Ceftin may result in the overgrowth of non-susceptible organisms. Monitor patients for signs of a superinfection.
• Liver Function: Monitor liver function tests if you have preexisting liver conditions or those on prolonged therapy.

Storage Instructions

• Store Ceftin tablets at room temperature, 20°C to 25°C (68°F to 77°F). 

• Protect from moisture and light. 

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/050672s029s032lbl.pdf