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Xalatan Preservative Free (latanoprost)

Indications

• Open-Angle Glaucoma: Used to reduce elevated intraocular pressure in patients with open-angle glaucoma.
• Ocular Hypertension: Helps lower high pressure in the eye, which can prevent blindness.

Ingredients

• Active Ingredients: Latanoprost
• Inactive Ingredients: Sodium chloride, Sodium dihydrogen phosphate monohydrate, Disodium phosphate anhydrous, Water for injection

Dosage and Administration

• Administer Xalatan as prescribed by your doctor, typically one drop in the affected eye(s) once daily in the evening.
• Wash your hands before and after using the eye drops.
• Tilt your head back and pull down the lower eyelid to create a small pocket before applying the drop.
• Use the single-dose container immediately after opening and discard any remaining solution.
• Do not use more than one drop in the affected eye(s) per day.
• Avoid touching the tip of the container to any surface to prevent contamination.
• Do not use if the solution changes color or becomes cloudy.
• Do not let the dropper tip come into contact with your eye or any other surface.

Mechanism of Action

Xalatan contains latanoprost, a prostaglandin analog. It works by increasing the outflow of aqueous humor from the eye, which reduces intraocular pressure. This helps prevent damage to the optic nerve and loss of vision.

Contraindications

• If you are allergic to latanoprost or any other ingredients in the solution.
• If you have a history of severe eye infections or eye conditions without proper medical supervision.

Side Effects

Common Side Effects:

• Blurred vision
• Eye redness
• Sensation of a foreign body in the eye
• Increased pigmentation of the iris
• Eyelash changes (thicker, longer, darker)

Serious Side Effects:

• Severe eye pain or discomfort
• Vision changes
• Eye swelling or discharge
• Severe allergic reactions (rash, itching, swelling, dizziness, difficulty breathing)
• Increased intraocular pressure

Precautions

• Inform your doctor if you have a history of eye conditions, surgeries, or any other medical conditions.
• Regularly monitor your intraocular pressure while using Xalatan.
• Discuss all your medications with your doctor to avoid potential interactions.
• Report any unusual symptoms or severe side effects to your doctor immediately.
• Avoid using contact lenses while applying the drops; wait at least 15 minutes after application before reinserting them.
• If using other eye medications, wait at least 5 minutes between applying each medication.

Storage Instructions

• Store Xalatan single dose containers in the refrigerator before opening.
• Once a container is opened, it can be stored at room temperature, away from light, for up to 6 weeks.
• Keep the containers in their original packaging to protect from light and moisture.
• Keep out of reach of children and pets.

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References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020597s044lbl.pdf