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Alrex (loteprednol etabonate)

Indications

• Alrex is used to treat eye inflammation caused by allergies.
• It helps relieve symptoms such as redness, itching, and swelling in the eyes.
• Alrex is effective for short-term treatment of seasonal allergic conjunctivitis.

Dosage and Administration

• Use Alrex exactly as prescribed by your doctor, typically one drop in the affected eye(s) four times daily.
• Shake the bottle well before each use.
• Wash your hands before using the eye drops to avoid contamination.
• Tilt your head back, look upward, and pull down the lower eyelid to create a small pocket before applying the drop.
• Close your eyes for 1-2 minutes after applying the drop to allow the medication to be absorbed.
• Follow your doctor’s instructions regarding the duration of use, usually not more than 2 weeks.
• Do not touch the dropper tip on any surface, including your eye, to avoid contamination.
• Avoid using Alrex if the solution changes color or becomes cloudy.
• Do not share your eye drops with others, even if they have similar symptoms.
• Avoid wearing contact lenses if your eyes are red; if you must wear them, remove them before applying Alrex and wait at least 15 minutes before reinserting them.
• Do not stop using Alrex abruptly without consulting your doctor, as this could worsen your condition.

Mechanism of Action

Alrex contains Loteprednol Etabonate, a corticosteroid. It works by inhibiting the release of substances in the body that cause inflammation. This action helps to reduce redness, swelling, and itching in the eyes caused by allergic reactions.

Contraindications

• Do not use Alrex if you are allergic to Loteprednol or any of its ingredients.
• Avoid using Alrex if you have a viral, fungal, or bacterial infection of the eye without consulting your doctor.
• Do not use Alrex if you have a history of herpes simplex infection in the eye.

Side Effects

Common Side Effects:

• Mild burning or stinging in the eye
• Dry eyes
• Watery eyes
• Headache

Serious Side Effects:

• Severe allergic reactions, including rash, itching, swelling, severe dizziness, and trouble breathing
• Eye pain or swelling
• Vision changes
• Signs of eye infection, such as increased redness, swelling, or discharge

Precautions

• Inform your doctor about all other medications you are using, including over-the-counter products and supplements.
• Notify your doctor if you have a history of glaucoma, cataracts, or other eye conditions.
• Use caution if you are pregnant, planning to become pregnant, or breastfeeding, and discuss the risks and benefits with your doctor.
• Avoid touching your eyes with your hands frequently to reduce the risk of infection.
• If you experience severe side effects or signs of an allergic reaction, seek medical attention immediately.

Storage Instructions

• Store Alrex at room temperature, between 15°C to 25°C (59°F to 77°F).
• Keep the bottle tightly closed when not in use.
• Store Alrex out of reach of children and pets.
• Protect the eye drops from light and moisture.

References

https://www.accessdata.fda.gov/drugsatfda_docs/nda/98/20-803_ALREX_PRNTLBL.PDF