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Atopica (cyclosporine)

Indications

• Atopica is used to treat atopic dermatitis (eczema) in dogs.
• It helps manage chronic allergic dermatitis and provides relief from itching and inflammation.
• Atopica can be prescribed to prevent organ rejection in transplant recipients in veterinary medicine.

Dosage and Administration

• Administer Atopica exactly as prescribed by your veterinarian, usually once daily.
• Give the capsules orally, with or without food, but it’s best given on an empty stomach for optimal absorption.
• Ensure your pet completes the entire course of medication even if symptoms improve.
• Do not give more than the prescribed dose.
• Avoid giving Atopica if your pet is allergic to cyclosporine or any of its ingredients.
• Do not stop administering Atopica abruptly without consulting your veterinarian.
• Avoid using Atopica in pets with known malignancies or a history of cancer.
• Do not allow your pet to eat or drink grapefruit products while on Atopica, as it can interfere with the medication.

Mechanism of Action

Atopica contains cyclosporine, an immunosuppressive agent. It works by inhibiting the activity of certain immune cells that cause inflammation and itching in allergic skin conditions. By modulating the immune response, Atopica helps reduce the symptoms of atopic dermatitis and improves the quality of life for pets.

Contraindications

• Do not use Atopica if your pet is allergic to cyclosporine or any of its ingredients.
• Avoid using Atopica in pets with a history of cancer or malignant conditions.
• Do not administer Atopica to pets with known liver or kidney disease without consulting your veterinarian.
• Avoid using Atopica in pets with uncontrolled infections.

Side Effects

Common Side Effects

• Vomiting
• Diarrhea
• Loss of appetite
• Lethargy
• Gingival hyperplasia (overgrowth of the gums)

Serious Side Effects

• Severe allergic reactions, including rash, itching, swelling, severe dizziness, and trouble breathing
• Signs of liver problems, such as yellowing of the skin or eyes, dark urine
• Signs of kidney problems, such as changes in urine output
• Unusual bleeding or bruising
• New or worsening infections

Precautions

• Inform your veterinarian about all other medications your pet is using, including over-the-counter products and supplements.
• Notify your veterinarian if your pet has a history of liver or kidney disease, infections, or immune disorders.
• Use caution if your pet is pregnant, planning to become pregnant, or nursing.
• Monitor your pet for any signs of infection or unusual symptoms and report them to your veterinarian.
• If your pet experiences severe side effects or signs of an allergic reaction, seek veterinary attention immediately.

Storage Instructions

• Store Atopica at room temperature, between 15°C to 30°C (59°F to 86°F).
• Keep the capsules in their original container, tightly closed.
• Store Atopica out of reach of children and pets.

References

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=99642708-0a9f-4ff0-bc08-f2b18691927e