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Periactin (cyproheptadine)

Indications

• Used to relieve symptoms of allergies, such as hay fever, rhinitis, and urticaria (hives).
• Prescribed to help stimulate appetite in underweight patients or those experiencing appetite loss due to medical conditions.
• Can be used to manage symptoms of migraines and other vascular headaches.

Dosage and Administration

• Take the tablet exactly as prescribed by your doctor.
• Swallow the tablet whole with a full glass of water.
• Take with or without food, depending on your doctor’s instructions.
• Take a missed dose as soon as you remember.
• Follow your doctor’s instructions for the dosing schedule, especially for appetite stimulation or allergy management.
• Do not exceed the prescribed dose.
• Do not crush or chew the tablet.
• Do not use the tablet if you are allergic to cyproheptadine or any of its ingredients.
• Do not consume alcohol while taking this medication, as it can increase drowsiness.
• Do not operate heavy machinery or drive until you know how the medication affects you, as it can cause drowsiness and dizziness.

Mechanism of Action

Periactin (Cyproheptadine) is an antihistamine that works by blocking histamine and serotonin receptors in the body. By doing so, it helps to reduce allergy symptoms and stimulates appetite by influencing the brain’s feeding center.

Contraindications

• Allergic Reaction: Do not use the tablets if you are allergic to Cyproheptadine or any of the ingredients in the tablet.
• Glaucoma: Avoid using the medication if you have narrow-angle glaucoma, as it may worsen the condition.
• MAOI Use: Do not take this medication if you are currently using or have recently used a monoamine oxidase inhibitor (MAOI) within the last 14 days.
• Newborns and Premature Infants: Not recommended for use in newborn or premature infants.

Side Effects

Common Side Effects:

• Drowsiness
• Dizziness
• Dry mouth
• Blurred vision
• Constipation
• Increased appetite and weight gain

Serious Side Effects:

• Confusion or hallucinations
• Severe allergic reactions (rash, itching, swelling)
• Difficulty urinating
• Fast or irregular heartbeat
• Severe dizziness or fainting

Precautions

• Inform about Medical History: Tell your doctor if you have a history of asthma, heart disease, high blood pressure, thyroid problems, or urinary retention.
• Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
• Avoid Dehydration: Drink plenty of fluids to avoid dehydration, especially if you experience dry mouth.
• Regular Monitoring: Attend regular check-ups to monitor your progress and any potential side effects.

Storage Instructions

• Keep the tablets at a temperature between 68°F and 77°F (20°C to 25°C).
• Store in a dry place, away from excessive moisture and light.
• Ensure the medication is stored securely away from children and pets.
• Dispose of unused or expired tablets properly, following local regulations or pharmacy guidelines.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/087056s045lbl.pdf