Are you Looking to Buy Macrodantin (Nitrofurantoin Macrocrystal) from PrescriptionPoint.

Macrodantin (nitrofurantoin) 

Indications 

Macrodantin helps treat and prevent urinary tract infections caused by certain bacteria. 

Dosage and Administration

• Take Macrodantin exactly as prescribed by your doctor. 
• Swallow the capsules whole with a full glass of water, with or without food. 
• Take the medication at evenly spaced intervals to maintain a constant level in the bloodstream. 
• Complete the full course of treatment even if you feel better, unless otherwise directed by your doctor. 
• Do not crush, chew, or open the capsules. 
• Do not take more than the prescribed dose. 
• Do not use Macrodantin to treat viral infections such as the common cold or flu. 
• Avoid taking antacids containing magnesium trisilicate while using Macrodantin, as it may reduce its effectiveness. 

Mechanism of Action 

Nitrofurantoin is an antibiotic that works by interfering with the production of bacterial proteins and DNA, ultimately leading to bacterial cell death. It is specifically effective against certain types of bacteria commonly found in urinary tract infections. 

Contraindications 

• Allergy to Nitrofurantoin: Do not use if you have a known hypersensitivity to nitrofurantoin or any of the ingredients in Macrodantin. 
• Severe Kidney Disease: Avoid use in patients with severe renal impairment (creatinine clearance below 60 mL/min). 
• Pregnancy at Term: Do not use near term (38 to 42 weeks of gestation), at the onset of labor, or during labor and delivery, as it may cause hemolytic anemia in the newborn. 
• Infants under One Month Old: Not recommended for use in infants younger than one month old due to the risk of neonatal hemolytic anemia. 

Side Effects 

Common Side Effects 

• Nausea 
• Vomiting 
• Diarrhea 
• Headache 
• Dizziness 

Serious Side Effects 

• Severe allergic reactions (rash, itching, swelling) 
• Difficulty breathing 
• Chest pain 
• Yellowing of the skin or eyes (jaundice) 
• Dark urine 
• Persistent cough or trouble breathing 

Precautions 

• Inform Your Doctor About All Medications: Ensure your doctor knows about all the medications you are taking to avoid drug interactions. 
• Monitor for Signs of Liver or Lung Problems: Report any symptoms such as jaundice, dark urine, persistent cough, or trouble breathing to your doctor. 
• Pregnancy and Breastfeeding: Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. 
• Avoid Prolonged Use: Long-term use of Macrodantin may increase the risk of developing bacterial resistance. 

Storage Instructions 

• Store at room temperature, between 20°C to 25°C (68°F to 77°F). 
• Protect from moisture and light. 
• Keep in the original container tightly closed. 
• Keep out of reach of children and pets. 
• Do not use after the expiration date on the container. 

References 

https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/016620s072lbl.pdf